While inclined going in to treat this as a throwaway film, Anne Hathaway’s bare-it-all performance was so compelling that I was mesmerized right up to the cliche of an ending. Jake Gyllenhaal’s low-key charm was also easy on the eyes and mind, seducing the viewer along with every woman onscreen. The corporate shenanigans verged on Up in the Air or even The Office, but representing a real company, Pfizer, gave the proceedings a patina of credibility. What kept this, though, from being a standard Julie Roberts/Hugh Grant rom-com, and belied the publicity poster, was the fundamental question it posed: should two people commit to a relationship when one of them has a debilitating physical condition that will only get worse.